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Hit Follow up Support

Hit Follow up Support
With our quality screening libraries,  services and hit confirmation process we guarantee the success of a hit finding campaign. Please try our  support in following-up the hits identified after screening of our Compound Libraries. 

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With our quality screening libraries, services and hit confirmation process we guarantee the success of a hit finding campaign. Please try our  support in following-up hits identified after screening our Compound Libraries. 

    • Hit Confirmation: dry samples resupplied from the same batch
    • Analogs: search within over 1,6M stock Screening Collection and immediate proposal of synthesis de novo IP clean analogues. Enumeration of new hit follow-up libraries. 
    • Resynthesis: within 3-4 weeks. All synthetic protocols are available.

Hit Confirmation 

    • Resupply from the same batch 
    • Quality control
    • HPLC purification, chiral separation 
    • Resynthesis and structure confirmation 

Hit Expansion

    • Analogs in Screening Collection, new IP clean chemical space 
    • Follow-up libraries design and enumeration of new libraries
    • In silico screening services: Pharmacophore modeling and docking calculation. 

Hit to Lead 

    • FTE-based Chemistry support 
    • ADME panel
    • PK studies
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