0388-0127 Screening compound: 1-benzyl-3,3-dimethyl-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine]

0388-0127 Screening compound: 1-benzyl-3,3-dimethyl-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine]
0388-0127 Screening compound: 1-benzyl-3,3-dimethyl-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine] alternative view

Chemical Structure Depiction of ChemDiv screening compound 0388-0127
1-benzyl-3,3-dimethyl-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine]

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

0388-0127

Molecular Formula

C28H24N2O (C28 H24 N2 O)

Compound Name

1-benzyl-3,3-dimethyl-1,3-dihydrospiro[indole-2,3'-naphtho[2,1-b][1,4]oxazine]

IUPAC name

1-benzyl-33-dimethyl-13-dihydrospiro[indole-23'-naphtho[21-b][14]oxazine]

SMILES

CC1(C)c(cccc2)c2N(Cc2ccccc2)C11Oc(ccc2ccccc22)c2N=C1

InChI

InChI=1S/C28H24N2O/c1-27(2)23-14-8-9-15-24(23)30(18-20-10-4-3-5-11-20)28(27)19-29-26-22-13-7-6-12-21(22)16-17-25(26)31-28/h3-17,19H,18H2,1-2H3/t28-/m1/s1

InChI Key

YVYVCXOQZYPIOP-MUUNZHRXSA-N

MDL Number (MFCD)

MFCD00329490

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.51

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

7.017

Distribution Coefficient, logD

7.017

Water Solubility, LogSw

-6.85

Polar Surface Area

14.903

Acid Dissociation Constant (pKa)

25.97

Base Dissociation Constant (pKb)

-0.16

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

17.90

0388-0127 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with 0388-0127 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 0388-0127?
Check Price and Availability of 0388-0127, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 0388-0127 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 0388-0127
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 0388-0127
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 0388-0127 available by request