0485-0038 Screening compound: N-[4-(4-methylphenyl)-5-phenyl-1,3-thiazol-2-yl]-2-phenylacetamide

0485-0038 Screening compound: N-[4-(4-methylphenyl)-5-phenyl-1,3-thiazol-2-yl]-2-phenylacetamide
0485-0038 Screening compound: N-[4-(4-methylphenyl)-5-phenyl-1,3-thiazol-2-yl]-2-phenylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 0485-0038
N-[4-(4-methylphenyl)-5-phenyl-1,3-thiazol-2-yl]-2-phenylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

0485-0038

Molecular Formula

C24H20N2OS (C24 H20 N2 OS)

Compound Name

N-[4-(4-methylphenyl)-5-phenyl-1,3-thiazol-2-yl]-2-phenylacetamide

IUPAC name

N-[4-(4-methylphenyl)-5-phenyl-13-thiazol-2-yl]-2-phenylacetamide

SMILES

Cc(cc1)ccc1-c1c(-c2ccccc2)sc(NC(Cc2ccccc2)=O)n1

InChI

InChI=1S/C24H20N2OS/c1-17-12-14-19(15-13-17)22-23(20-10-6-3-7-11-20)28-24(26-22)25-21(27)16-18-8-4-2-5-9-18/h2-15H,16H2,1H3,(H,25,26,27)

InChI Key

RMHQCBOIZVAHCA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01535816

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.5

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.045

Distribution Coefficient, logD

6.045

Water Solubility, LogSw

-5.62

Polar Surface Area

33.390

Acid Dissociation Constant (pKa)

12.63

Base Dissociation Constant (pKb)

-0.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

0485-0038 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Proteases
  • Kinases
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 0485-0038 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 0485-0038?
Check Price and Availability of 0485-0038, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 0485-0038 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 0485-0038
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 0485-0038
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 0485-0038 available by request