0590-0220 Screening compound: N-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-2,4-dimethoxybenzamide

0590-0220 Screening compound: N-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-2,4-dimethoxybenzamide
0590-0220 Screening compound: N-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-2,4-dimethoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 0590-0220
N-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-2,4-dimethoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

0590-0220

Molecular Formula

C24H20N2O3S (C24 H20 N2 O3 S)

Compound Name

N-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-2,4-dimethoxybenzamide

IUPAC name

N-(4-{[11'-biphenyl]-4-yl}-13-thiazol-2-yl)-24-dimethoxybenzamide

SMILES

COc(cc1)cc(OC)c1C(Nc1nc(-c(cc2)ccc2-c2ccccc2)cs1)=O

InChI

InChI=1S/C24H20N2O3S/c1-28-19-12-13-20(22(14-19)29-2)23(27)26-24-25-21(15-30-24)18-10-8-17(9-11-18)16-6-4-3-5-7-16/h3-15H,1-2H3,(H,25,26,27)

InChI Key

BORZYJDERKAKHG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00805504

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.382

Distribution Coefficient, logD

6.376

Water Solubility, LogSw

-5.66

Polar Surface Area

48.007

Acid Dissociation Constant (pKa)

9.26

Base Dissociation Constant (pKb)

-1.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

0590-0220 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-infective Library (19449 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with 0590-0220 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 0590-0220?
Check Price and Availability of 0590-0220, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 0590-0220 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 0590-0220
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 0590-0220
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 0590-0220 available by request