0685-0181 Screening compound: (2E)-2-[(2Z)-2-[(furan-2-yl)methylidene]hydrazin-1-ylidene]-1,3-thiazolidin-4-one

0685-0181 Screening compound: (2E)-2-[(2Z)-2-[(furan-2-yl)methylidene]hydrazin-1-ylidene]-1,3-thiazolidin-4-one
0685-0181 Screening compound: (2E)-2-[(2Z)-2-[(furan-2-yl)methylidene]hydrazin-1-ylidene]-1,3-thiazolidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 0685-0181
(2E)-2-[(2Z)-2-[(furan-2-yl)methylidene]hydrazin-1-ylidene]-1,3-thiazolidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

0685-0181

Molecular Formula

C8H7N3O2S (C8 H7 N3 O2 S)

Compound Name

(2E)-2-[(2Z)-2-[(furan-2-yl)methylidene]hydrazin-1-ylidene]-1,3-thiazolidin-4-one

IUPAC name

(2E)-2-[(2Z)-2-[(furan-2-yl)methylidene]hydrazin-1-ylidene]-13-thiazolidin-4-one

SMILES

O=C(CS1)N/C1=N\N=C/c1ccco1

InChI

InChI=1S/C8H7N3O2S/c12-7-5-14-8(10-7)11-9-4-6-2-1-3-13-6/h1-4H,5H2,(H,10,11,12)

InChI Key

QDZWHNCXVHRCKP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00990830

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

209.23

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

0.965

Distribution Coefficient, logD

0.738

Water Solubility, LogSw

-2.19

Polar Surface Area

52.382

Acid Dissociation Constant (pKa)

7.56

Base Dissociation Constant (pKb)

2.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

0685-0181 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Frequent Hitters Library (7624 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases
Structure:
  • Pool

References: we are preparing a list of scientific research reports with 0685-0181 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 0685-0181?
Check Price and Availability of 0685-0181, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 0685-0181 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 0685-0181
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 0685-0181
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 0685-0181 available by request