1000-0247 Screening compound: N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-3,4-difluorobenzamide

1000-0247 Screening compound: N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-3,4-difluorobenzamide
1000-0247 Screening compound: N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-3,4-difluorobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1000-0247
N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-3,4-difluorobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1000-0247

Molecular Formula

C16H8Cl2F2N2OS (C16 H8 Cl2 F2 N2 OS)

Compound Name

N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-3,4-difluorobenzamide

IUPAC name

N-[4-(34-dichlorophenyl)-13-thiazol-2-yl]-34-difluorobenzamide

SMILES

O=C(c(cc1)cc(F)c1F)Nc1nc(-c(cc2)cc(Cl)c2Cl)cs1

InChI

InChI=1S/C16H8Cl2F2N2OS/c17-10-3-1-8(5-11(10)18)14-7-24-16(21-14)22-15(23)9-2-4-12(19)13(20)6-9/h1-7H,(H,21,22,23)

InChI Key

LPVZORXUZUYNIY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01930766

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.22

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.175

Distribution Coefficient, logD

6.134

Water Solubility, LogSw

-6.50

Polar Surface Area

33.104

Acid Dissociation Constant (pKa)

8.40

Base Dissociation Constant (pKb)

-0.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

1000-0247 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Proline Kinase Library (2105 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with 1000-0247 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1000-0247?
Check Price and Availability of 1000-0247, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1000-0247 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1000-0247
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1000-0247
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1000-0247 available by request