1185-0005 Screening compound: (2Z)-4-(3,4-dimethoxyphenyl)-N,3-diphenyl-2,3-dihydro-1,3-thiazol-2-imine

1185-0005 Screening compound: (2Z)-4-(3,4-dimethoxyphenyl)-N,3-diphenyl-2,3-dihydro-1,3-thiazol-2-imine
1185-0005 Screening compound: (2Z)-4-(3,4-dimethoxyphenyl)-N,3-diphenyl-2,3-dihydro-1,3-thiazol-2-imine alternative view

Chemical Structure Depiction of ChemDiv screening compound 1185-0005
(2Z)-4-(3,4-dimethoxyphenyl)-N,3-diphenyl-2,3-dihydro-1,3-thiazol-2-imine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1185-0005

Molecular Formula

C23H20N2O2S (C23 H20 N2 O2 S)

Compound Name

(2Z)-4-(3,4-dimethoxyphenyl)-N,3-diphenyl-2,3-dihydro-1,3-thiazol-2-imine

IUPAC name

(2Z)-4-(34-dimethoxyphenyl)-N3-diphenyl-23-dihydro-13-thiazol-2-imine

SMILES

COc(ccc(C(N1c2ccccc2)=CS/C1=N\c1ccccc1)c1)c1OC

InChI

InChI=1S/C23H20N2O2S/c1-26-21-14-13-17(15-22(21)27-2)20-16-28-23(24-18-9-5-3-6-10-18)25(20)19-11-7-4-8-12-19/h3-16H,1-2H3

InChI Key

BOJTXPXBSLEUBC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00683521

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.997

Distribution Coefficient, logD

4.997

Water Solubility, LogSw

-4.82

Polar Surface Area

25.952

Acid Dissociation Constant (pKa)

33.29

Base Dissociation Constant (pKb)

-1.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

1185-0005 in Drug Discovery

Included in Screening Libraries

Frequent Hitters Library (7624 compounds)

Proline Kinase Library (2105 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 1185-0005 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1185-0005?
Check Price and Availability of 1185-0005, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1185-0005 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1185-0005
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1185-0005
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1185-0005 available by request