1187-0161 Screening compound: 1-(2,5-diphenyl-1,3-thiazol-4-yl)-4-(methylsulfanyl)-1,2-dihydropyrimidin-2-one

1187-0161 Screening compound: 1-(2,5-diphenyl-1,3-thiazol-4-yl)-4-(methylsulfanyl)-1,2-dihydropyrimidin-2-one
1187-0161 Screening compound: 1-(2,5-diphenyl-1,3-thiazol-4-yl)-4-(methylsulfanyl)-1,2-dihydropyrimidin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 1187-0161
1-(2,5-diphenyl-1,3-thiazol-4-yl)-4-(methylsulfanyl)-1,2-dihydropyrimidin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1187-0161

Molecular Formula

C20H15N3OS2 (C20 H15 N3 OS2)

Compound Name

1-(2,5-diphenyl-1,3-thiazol-4-yl)-4-(methylsulfanyl)-1,2-dihydropyrimidin-2-one

IUPAC name

1-(25-diphenyl-13-thiazol-4-yl)-4-(methylsulfanyl)-12-dihydropyrimidin-2-one

SMILES

CSC(C=CN1c2c(-c3ccccc3)sc(-c3ccccc3)n2)=NC1=O

InChI

InChI=1S/C20H15N3OS2/c1-25-16-12-13-23(20(24)21-16)18-17(14-8-4-2-5-9-14)26-19(22-18)15-10-6-3-7-11-15/h2-13H,1H3

InChI Key

POCKESXHTYIHID-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00195476

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.103

Distribution Coefficient, logD

5.052

Water Solubility, LogSw

-5.00

Polar Surface Area

34.153

Acid Dissociation Constant (pKa)

36.97

Base Dissociation Constant (pKb)

6.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.00

1187-0161 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Agro:
  • Agro
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 1187-0161 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1187-0161?
Check Price and Availability of 1187-0161, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1187-0161 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1187-0161
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1187-0161
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1187-0161 available by request