1187-1282 Screening compound: 2-[(2E)-2-[(2,4-dimethylphenyl)methylidene]hydrazin-1-yl]-4-(4-fluorophenyl)-1,3-thiazole

1187-1282 Screening compound: 2-[(2E)-2-[(2,4-dimethylphenyl)methylidene]hydrazin-1-yl]-4-(4-fluorophenyl)-1,3-thiazole
1187-1282 Screening compound: 2-[(2E)-2-[(2,4-dimethylphenyl)methylidene]hydrazin-1-yl]-4-(4-fluorophenyl)-1,3-thiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound 1187-1282
2-[(2E)-2-[(2,4-dimethylphenyl)methylidene]hydrazin-1-yl]-4-(4-fluorophenyl)-1,3-thiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1187-1282

Molecular Formula

C18H16FN3S (C18 H16 FN3 S)

Compound Name

2-[(2E)-2-[(2,4-dimethylphenyl)methylidene]hydrazin-1-yl]-4-(4-fluorophenyl)-1,3-thiazole

IUPAC name

2-[(2E)-2-[(24-dimethylphenyl)methylidene]hydrazin-1-yl]-4-(4-fluorophenyl)-13-thiazole

SMILES

Cc1cc(C)c(/C=N/Nc2nc(-c(cc3)ccc3F)cs2)cc1

InChI

InChI=1S/C18H16FN3S/c1-12-3-4-15(13(2)9-12)10-20-22-18-21-17(11-23-18)14-5-7-16(19)8-6-14/h3-11H,1-2H3,(H,21,22)

InChI Key

OSVQQQVHAIECEB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01531395

Chemical and Physical Properties

Saltdata

HBr

Molecular Weight

325.41

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.571

Distribution Coefficient, logD

6.571

Water Solubility, LogSw

-5.81

Polar Surface Area

31.150

Acid Dissociation Constant (pKa)

14.90

Base Dissociation Constant (pKb)

2.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

1187-1282 in Drug Discovery

Included in Screening Libraries

Frequent Hitters Library (7624 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 1187-1282 chemical compound. It will be published here after verification.

Frequently Asked Questions

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What is the minimum amount of 1187-1282 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1187-1282
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1187-1282
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1187-1282 available by request