1218-2048 Screening compound: 4-methoxy-N'-[(E)-(3,4,5-trimethoxyphenyl)methylidene]benzohydrazide

1218-2048 Screening compound: 4-methoxy-N'-[(E)-(3,4,5-trimethoxyphenyl)methylidene]benzohydrazide
1218-2048 Screening compound: 4-methoxy-N'-[(E)-(3,4,5-trimethoxyphenyl)methylidene]benzohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1218-2048
4-methoxy-N'-[(E)-(3,4,5-trimethoxyphenyl)methylidene]benzohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1218-2048

Molecular Formula

C18H20N2O5 (C18 H20 N2 O5)

Compound Name

4-methoxy-N'-[(E)-(3,4,5-trimethoxyphenyl)methylidene]benzohydrazide

IUPAC name

4-methoxy-N'-[(E)-(345-trimethoxyphenyl)methylidene]benzohydrazide

SMILES

COc(cc1)ccc1C(N/N=C/c(cc1OC)cc(OC)c1OC)=O

InChI

InChI=1S/C18H20N2O5/c1-22-14-7-5-13(6-8-14)18(21)20-19-11-12-9-15(23-2)17(25-4)16(10-12)24-3/h5-11H,1-4H3,(H,20,21)

InChI Key

VVSMZYVQEGJDGA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00593976

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

344.37

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.823

Distribution Coefficient, logD

2.822

Water Solubility, LogSw

-3.49

Polar Surface Area

66.076

Acid Dissociation Constant (pKa)

10.02

Base Dissociation Constant (pKb)

1.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

1218-2048 in Drug Discovery

Included in Screening Libraries

Frequent Hitters Library (7624 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 1218-2048 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1218-2048?
Check Price and Availability of 1218-2048, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1218-2048 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1218-2048
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1218-2048
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1218-2048 available by request