1348-0642 Screening compound: N'-[(3Z)-7-bromo-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-4-hydroxybenzohydrazide

1348-0642 Screening compound: N'-[(3Z)-7-bromo-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-4-hydroxybenzohydrazide
1348-0642 Screening compound: N'-[(3Z)-7-bromo-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-4-hydroxybenzohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1348-0642
N'-[(3Z)-7-bromo-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-4-hydroxybenzohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1348-0642

Molecular Formula

C16H12BrN3O3 (C16 H12 BrN3 O3)

Compound Name

N'-[(3Z)-7-bromo-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-4-hydroxybenzohydrazide

IUPAC name

N'-[(3Z)-7-bromo-5-methyl-2-oxo-23-dihydro-1H-indol-3-ylidene]-4-hydroxybenzohydrazide

SMILES

Cc(cc1/C2=N/NC(c(cc3)ccc3O)=O)cc(Br)c1NC2=O

InChI

InChI=1S/C16H12BrN3O3/c1-8-6-11-13(12(17)7-8)18-16(23)14(11)19-20-15(22)9-2-4-10(21)5-3-9/h2-7,21H,1H3,(H,20,22)(H,18,19,23)

InChI Key

MGQUXXZMWDPGNJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00565875

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.19

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.489

Distribution Coefficient, logD

2.374

Water Solubility, LogSw

-2.94

Polar Surface Area

74.729

Acid Dissociation Constant (pKa)

7.92

Base Dissociation Constant (pKb)

-0.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.30

1348-0642 in Drug Discovery

Included in Screening Libraries

Frequent Hitters Library (7624 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 1348-0642 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1348-0642?
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What is the minimum amount of 1348-0642 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1348-0642
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1348-0642
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1348-0642 available by request