1429-0008 Screening compound: N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]-2-(4-methoxyphenoxy)acetohydrazide

1429-0008 Screening compound: N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]-2-(4-methoxyphenoxy)acetohydrazide
1429-0008 Screening compound: N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]-2-(4-methoxyphenoxy)acetohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1429-0008
N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]-2-(4-methoxyphenoxy)acetohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1429-0008

Molecular Formula

C20H18N2O4 (C20 H18 N2 O4)

Compound Name

N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]-2-(4-methoxyphenoxy)acetohydrazide

IUPAC name

N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]-2-(4-methoxyphenoxy)acetohydrazide

SMILES

COc(cc1)ccc1OCC(N/N=C/c(c1ccccc1cc1)c1O)=O

InChI

InChI=1S/C20H18N2O4/c1-25-15-7-9-16(10-8-15)26-13-20(24)22-21-12-18-17-5-3-2-4-14(17)6-11-19(18)23/h2-12,23H,13H2,1H3,(H,22,24)

InChI Key

WSCMDUTZOFCORF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00636466

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.37

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.904

Distribution Coefficient, logD

3.902

Water Solubility, LogSw

-3.99

Polar Surface Area

66.660

Acid Dissociation Constant (pKa)

9.77

Base Dissociation Constant (pKb)

2.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

1429-0008 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 1429-0008 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1429-0008?
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What is the minimum amount of 1429-0008 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1429-0008
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1429-0008
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1429-0008 available by request