1486-1048 Screening compound: 1-{[(benzenesulfonyl)(4-chlorophenyl)carbamoyl]amino}-N-[3-(trifluoromethyl)phenyl]formamide

1486-1048 Screening compound: 1-{[(benzenesulfonyl)(4-chlorophenyl)carbamoyl]amino}-N-[3-(trifluoromethyl)phenyl]formamide
1486-1048 Screening compound: 1-{[(benzenesulfonyl)(4-chlorophenyl)carbamoyl]amino}-N-[3-(trifluoromethyl)phenyl]formamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1486-1048
1-{[(benzenesulfonyl)(4-chlorophenyl)carbamoyl]amino}-N-[3-(trifluoromethyl)phenyl]formamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1486-1048

Molecular Formula

C21H15ClF3N3O4S (C21 H15 ClF3 N3 O4 S)

Compound Name

1-{[(benzenesulfonyl)(4-chlorophenyl)carbamoyl]amino}-N-[3-(trifluoromethyl)phenyl]formamide

IUPAC name

1-{[(benzenesulfonyl)(4-chlorophenyl)carbamoyl]amino}-N-[3-(trifluoromethyl)phenyl]formamide

SMILES

O=C(NC(N(c(cc1)ccc1Cl)S(c1ccccc1)(=O)=O)=O)Nc1cc(C(F)(F)F)ccc1

InChI

InChI=1S/C21H15ClF3N3O4S/c22-15-9-11-17(12-10-15)28(33(31,32)18-7-2-1-3-8-18)20(30)27-19(29)26-16-6-4-5-14(13-16)21(23,24)25/h1-13H,(H2,26,27,29,30)

InChI Key

DHANXKQYOBPVQZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02084166

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.88

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.629

Distribution Coefficient, logD

5.627

Water Solubility, LogSw

-6.18

Polar Surface Area

77.758

Acid Dissociation Constant (pKa)

9.61

Base Dissociation Constant (pKb)

-5.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

1486-1048 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Frequent Hitters Library (7624 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Infections
  • Immune system
  • animal
Targets:
  • Kinases
  • Others
Structure:
  • Pool
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 1486-1048 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1486-1048?
Check Price and Availability of 1486-1048, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1486-1048 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1486-1048
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1486-1048
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1486-1048 available by request