1492-0552 Screening compound: 5-chloro-1-(2,5-diphenyl-1,3-oxazol-4-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

1492-0552 Screening compound: 5-chloro-1-(2,5-diphenyl-1,3-oxazol-4-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
1492-0552 Screening compound: 5-chloro-1-(2,5-diphenyl-1,3-oxazol-4-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound 1492-0552
5-chloro-1-(2,5-diphenyl-1,3-oxazol-4-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1492-0552

Molecular Formula

C19H12ClN3O3 (C19 H12 ClN3 O3)

Compound Name

5-chloro-1-(2,5-diphenyl-1,3-oxazol-4-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

5-chloro-1-(25-diphenyl-13-oxazol-4-yl)-1234-tetrahydropyrimidine-24-dione

SMILES

O=C(C(Cl)=CN1c2c(-c3ccccc3)oc(-c3ccccc3)n2)NC1=O

InChI

InChI=1S/C19H12ClN3O3/c20-14-11-23(19(25)22-17(14)24)16-15(12-7-3-1-4-8-12)26-18(21-16)13-9-5-2-6-10-13/h1-11H,(H,22,24,25)

InChI Key

BYDUFWXHOLLNJZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00520093

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.78

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.928

Distribution Coefficient, logD

3.830

Water Solubility, LogSw

-4.45

Polar Surface Area

57.999

Acid Dissociation Constant (pKa)

8.00

Base Dissociation Constant (pKb)

-4.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

1492-0552 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with 1492-0552 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1492-0552?
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What is the minimum amount of 1492-0552 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1492-0552
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1492-0552
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1492-0552 available by request