1543-0008 Screening compound: (5E)-3-(3-chlorophenyl)-5-{[4-(dimethylamino)phenyl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one

1543-0008 Screening compound: (5E)-3-(3-chlorophenyl)-5-{[4-(dimethylamino)phenyl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one
1543-0008 Screening compound: (5E)-3-(3-chlorophenyl)-5-{[4-(dimethylamino)phenyl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 1543-0008
(5E)-3-(3-chlorophenyl)-5-{[4-(dimethylamino)phenyl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1543-0008

Molecular Formula

C18H15ClN2OS2 (C18 H15 ClN2 OS2)

Compound Name

(5E)-3-(3-chlorophenyl)-5-{[4-(dimethylamino)phenyl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one

IUPAC name

(5E)-3-(3-chlorophenyl)-5-{[4-(dimethylamino)phenyl]methylidene}-2-sulfanylidene-13-thiazolidin-4-one

SMILES

CN(C)c1ccc(/C=C(\C(N2c3cccc(Cl)c3)=O)/SC2=S)cc1

InChI

InChI=1S/C18H15ClN2OS2/c1-20(2)14-8-6-12(7-9-14)10-16-17(22)21(18(23)24-16)15-5-3-4-13(19)11-15/h3-11H,1-2H3

InChI Key

RZYOMBYXRQPUFJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00523235

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.91

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.675

Distribution Coefficient, logD

4.675

Water Solubility, LogSw

-5.05

Polar Surface Area

18.636

Acid Dissociation Constant (pKa)

30.86

Base Dissociation Constant (pKb)

3.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

1543-0008 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

Frequent Hitters Library (7624 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
Agro:
  • Agro
Structure:
  • Pool

References: we are preparing a list of scientific research reports with 1543-0008 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1543-0008?
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What is the minimum amount of 1543-0008 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1543-0008
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1543-0008
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1543-0008 available by request