1762-0424 Screening compound: N-[2-chloro-5-(trifluoromethyl)phenyl]-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

1762-0424 Screening compound: N-[2-chloro-5-(trifluoromethyl)phenyl]-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
1762-0424 Screening compound: N-[2-chloro-5-(trifluoromethyl)phenyl]-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1762-0424
N-[2-chloro-5-(trifluoromethyl)phenyl]-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1762-0424

Molecular Formula

C19H9ClF6N4OS (C19 H9 ClF6 N4 OS)

Compound Name

N-[2-chloro-5-(trifluoromethyl)phenyl]-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

N-[2-chloro-5-(trifluoromethyl)phenyl]-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine-2-carboxamide

SMILES

O=C(c1nn2c(C(F)(F)F)cc(-c3cccs3)nc2c1)Nc(cc(C(F)(F)F)cc1)c1Cl

InChI

InChI=1S/C19H9ClF6N4OS/c20-10-4-3-9(18(21,22)23)6-11(10)28-17(31)13-8-16-27-12(14-2-1-5-32-14)7-15(19(24,25)26)30(16)29-13/h1-8H,(H,28,31)

InChI Key

BNWXFPMRFCKJAW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01077170

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.82

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.076

Distribution Coefficient, logD

5.959

Water Solubility, LogSw

-6.47

Polar Surface Area

41.809

Acid Dissociation Constant (pKa)

7.91

Base Dissociation Constant (pKb)

-2.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

1762-0424 in Drug Discovery

Included in Screening Libraries

Frequent Hitters Library (7624 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
Therapeutical areas:
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with 1762-0424 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1762-0424?
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What is the minimum amount of 1762-0424 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1762-0424
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1762-0424
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1762-0424 available by request