1778-2758 Screening compound: 2-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-1,2,3,4-tetrahydroisoquinoline

1778-2758 Screening compound: 2-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-1,2,3,4-tetrahydroisoquinoline
1778-2758 Screening compound: 2-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-1,2,3,4-tetrahydroisoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound 1778-2758
2-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-1,2,3,4-tetrahydroisoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1778-2758

Molecular Formula

C20H17ClN2O2 (C20 H17 ClN2 O2)

Compound Name

2-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-1,2,3,4-tetrahydroisoquinoline

IUPAC name

2-[3-(2-chlorophenyl)-5-methyl-12-oxazole-4-carbonyl]-1234-tetrahydroisoquinoline

SMILES

Cc1c(C(N(CC2)Cc3c2cccc3)=O)c(-c(cccc2)c2Cl)no1

InChI

InChI=1S/C20H17ClN2O2/c1-13-18(19(22-25-13)16-8-4-5-9-17(16)21)20(24)23-11-10-14-6-2-3-7-15(14)12-23/h2-9H,10-12H2,1H3

InChI Key

MRPXIBNDZZKHPH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00115372

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

352.82

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.956

Distribution Coefficient, logD

3.956

Water Solubility, LogSw

-4.55

Polar Surface Area

38.509

Acid Dissociation Constant (pKa)

24.26

Base Dissociation Constant (pKb)

-4.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

1778-2758 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

GABA Library (7115 compounds)

GPCR Targeted Library (31838 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Eye
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
  • Ion Channels
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 1778-2758 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1778-2758?
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What is the minimum amount of 1778-2758 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1778-2758
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1778-2758
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1778-2758 available by request