1805-1408 Screening compound: N'-[(3Z)-2-oxo-1-(2-phenylethyl)-2,3-dihydro-1H-indol-3-ylidene]-2,2-diphenylcyclopropane-1-carbohydrazide

1805-1408 Screening compound: N'-[(3Z)-2-oxo-1-(2-phenylethyl)-2,3-dihydro-1H-indol-3-ylidene]-2,2-diphenylcyclopropane-1-carbohydrazide
1805-1408 Screening compound: N'-[(3Z)-2-oxo-1-(2-phenylethyl)-2,3-dihydro-1H-indol-3-ylidene]-2,2-diphenylcyclopropane-1-carbohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1805-1408
N'-[(3Z)-2-oxo-1-(2-phenylethyl)-2,3-dihydro-1H-indol-3-ylidene]-2,2-diphenylcyclopropane-1-carbohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1805-1408

Molecular Formula

C32H27N3O2 (C32 H27 N3 O2)

Compound Name

N'-[(3Z)-2-oxo-1-(2-phenylethyl)-2,3-dihydro-1H-indol-3-ylidene]-2,2-diphenylcyclopropane-1-carbohydrazide

IUPAC name

N'-[(3Z)-2-oxo-1-(2-phenylethyl)-23-dihydro-1H-indol-3-ylidene]-22-diphenylcyclopropane-1-carbohydrazide

SMILES

O=C(C(C1)C1(c1ccccc1)c1ccccc1)N/N=C(/c(cccc1)c1N1CCc2ccccc2)\C1=O

InChI

InChI=1S/C32H27N3O2/c36-30(27-22-32(27,24-14-6-2-7-15-24)25-16-8-3-9-17-25)34-33-29-26-18-10-11-19-28(26)35(31(29)37)21-20-23-12-4-1-5-13-23/h1-19,27H,20-22H2,(H,34,36)/t27-/m1/s1

InChI Key

NZPZGRQDDUCLCR-HHHXNRCGSA-N

MDL Number (MFCD)

MFCD01537182

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.59

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.127

Distribution Coefficient, logD

5.099

Water Solubility, LogSw

-5.99

Polar Surface Area

49.548

Acid Dissociation Constant (pKa)

6.42

Base Dissociation Constant (pKb)

-0.86

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

15.60

1805-1408 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with 1805-1408 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1805-1408?
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What is the minimum amount of 1805-1408 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1805-1408
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1805-1408
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1805-1408 available by request