1805-1426 Screening compound: N'-[(E)-(3,4-dimethoxyphenyl)methylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide

1805-1426 Screening compound: N'-[(E)-(3,4-dimethoxyphenyl)methylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide
1805-1426 Screening compound: N'-[(E)-(3,4-dimethoxyphenyl)methylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1805-1426
N'-[(E)-(3,4-dimethoxyphenyl)methylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1805-1426

Molecular Formula

C23H21N5O3 (C23 H21 N5 O3)

Compound Name

N'-[(E)-(3,4-dimethoxyphenyl)methylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide

IUPAC name

N'-[(E)-(34-dimethoxyphenyl)methylidene]-2-[2-(pyridin-2-yl)-1H-13-benzodiazol-1-yl]acetohydrazide

SMILES

COc(ccc(/C=N/NC(Cn1c(-c2ncccc2)nc2c1cccc2)=O)c1)c1OC

InChI

InChI=1S/C23H21N5O3/c1-30-20-11-10-16(13-21(20)31-2)14-25-27-22(29)15-28-19-9-4-3-7-17(19)26-23(28)18-8-5-6-12-24-18/h3-14H,15H2,1-2H3,(H,27,29)

InChI Key

FWFBMZNCCLDFPG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01537185

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.126

Distribution Coefficient, logD

3.126

Water Solubility, LogSw

-3.24

Polar Surface Area

69.578

Acid Dissociation Constant (pKa)

10.63

Base Dissociation Constant (pKb)

3.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

1805-1426 in Drug Discovery

Included in Screening Libraries

Frequent Hitters Library (7624 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 1805-1426 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1805-1426?
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What is the minimum amount of 1805-1426 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1805-1426
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1805-1426
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1805-1426 available by request