1927-6742 Screening compound: (5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-(4-methylphenyl)-4,5-dihydro-1,3-thiazol-4-one

1927-6742 Screening compound: (5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-(4-methylphenyl)-4,5-dihydro-1,3-thiazol-4-one
1927-6742 Screening compound: (5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-(4-methylphenyl)-4,5-dihydro-1,3-thiazol-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 1927-6742
(5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-(4-methylphenyl)-4,5-dihydro-1,3-thiazol-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1927-6742

Molecular Formula

C18H15NO3S (C18 H15 NO3 S)

Compound Name

(5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-(4-methylphenyl)-4,5-dihydro-1,3-thiazol-4-one

IUPAC name

(5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-(4-methylphenyl)-45-dihydro-13-thiazol-4-one

SMILES

Cc(cc1)ccc1C(S/C1=C\c(cc2)cc(OC)c2O)=NC1=O

InChI

InChI=1S/C18H15NO3S/c1-11-3-6-13(7-4-11)18-19-17(21)16(23-18)10-12-5-8-14(20)15(9-12)22-2/h3-10,20H,1-2H3

InChI Key

SYMWDHQZCMAQBC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01455157

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

325.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.180

Distribution Coefficient, logD

3.175

Water Solubility, LogSw

-3.03

Polar Surface Area

46.466

Acid Dissociation Constant (pKa)

9.35

Base Dissociation Constant (pKb)

0.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

1927-6742 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

Frequent Hitters Library (7624 compounds)

Carbonic Anhydrase II Library (4939 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
Agro:
  • Agro
Structure:
  • Pool

References: we are preparing a list of scientific research reports with 1927-6742 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1927-6742?
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What is the minimum amount of 1927-6742 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1927-6742
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1927-6742
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1927-6742 available by request