2043-4132 Screening compound: N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-[1,1'-biphenyl]-4-carboxamide

2043-4132 Screening compound: N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-[1,1'-biphenyl]-4-carboxamide
2043-4132 Screening compound: N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-[1,1'-biphenyl]-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 2043-4132
N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-[1,1'-biphenyl]-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2043-4132

Molecular Formula

C23H18N2OS (C23 H18 N2 OS)

Compound Name

N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-[1,1'-biphenyl]-4-carboxamide

IUPAC name

N-[4-(4-methylphenyl)-13-thiazol-2-yl]-[11'-biphenyl]-4-carboxamide

SMILES

Cc(cc1)ccc1-c1csc(NC(c(cc2)ccc2-c2ccccc2)=O)n1

InChI

InChI=1S/C23H18N2OS/c1-16-7-9-19(10-8-16)21-15-27-23(24-21)25-22(26)20-13-11-18(12-14-20)17-5-3-2-4-6-17/h2-15H,1H3,(H,24,25,26)

InChI Key

QGQWVBKDEOLKBY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01327899

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.47

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.780

Distribution Coefficient, logD

6.780

Water Solubility, LogSw

-5.98

Polar Surface Area

32.833

Acid Dissociation Constant (pKa)

10.32

Base Dissociation Constant (pKb)

0.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.30

2043-4132 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Epigenetics Focused Set (26518 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Kinases
  • Proteases
  • Ion Channels
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with 2043-4132 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2043-4132?
Check Price and Availability of 2043-4132, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2043-4132 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2043-4132
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2043-4132
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2043-4132 available by request