2123-0316 Screening compound: 3-bromo-5-(4-bromothiophen-2-yl)-N-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

2123-0316 Screening compound: 3-bromo-5-(4-bromothiophen-2-yl)-N-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
2123-0316 Screening compound: 3-bromo-5-(4-bromothiophen-2-yl)-N-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 2123-0316
3-bromo-5-(4-bromothiophen-2-yl)-N-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2123-0316

Molecular Formula

C18H8Br2ClF3N4OS (C18 H8 Br2 ClF3 N4 OS)

Compound Name

3-bromo-5-(4-bromothiophen-2-yl)-N-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

3-bromo-5-(4-bromothiophen-2-yl)-N-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine-2-carboxamide

SMILES

O=C(c1nn2c(C(F)(F)F)cc(-c3cc(Br)cs3)nc2c1Br)Nc(cc1)ccc1Cl

InChI

InChI=1S/C18H8Br2ClF3N4OS/c19-8-5-12(30-7-8)11-6-13(18(22,23)24)28-16(26-11)14(20)15(27-28)17(29)25-10-3-1-9(21)2-4-10/h1-7H,(H,25,29)

InChI Key

ZQWZJTMDBGOGQE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01079660

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

580.61

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.691

Distribution Coefficient, logD

6.687

Water Solubility, LogSw

-6.69

Polar Surface Area

43.824

Acid Dissociation Constant (pKa)

9.46

Base Dissociation Constant (pKb)

-2.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.60

2123-0316 in Drug Discovery

Included in Screening Libraries

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Ion Channels
  • Kinases

References: we are preparing a list of scientific research reports with 2123-0316 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2123-0316?
Check Price and Availability of 2123-0316, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2123-0316 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2123-0316
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2123-0316
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2123-0316 available by request