2144-1018 Screening compound: 4-[(2E)-2-({1-[(4-chlorophenyl)methyl]-1H-indol-3-yl}methylidene)hydrazin-1-yl]-N-(2,3-dimethylphenyl)-6-(4-methylpiperidin-1-yl)-1,3,5-triazin-2-amine

2144-1018 Screening compound: 4-[(2E)-2-({1-[(4-chlorophenyl)methyl]-1H-indol-3-yl}methylidene)hydrazin-1-yl]-N-(2,3-dimethylphenyl)-6-(4-methylpiperidin-1-yl)-1,3,5-triazin-2-amine
2144-1018 Screening compound: 4-[(2E)-2-({1-[(4-chlorophenyl)methyl]-1H-indol-3-yl}methylidene)hydrazin-1-yl]-N-(2,3-dimethylphenyl)-6-(4-methylpiperidin-1-yl)-1,3,5-triazin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 2144-1018
4-[(2E)-2-({1-[(4-chlorophenyl)methyl]-1H-indol-3-yl}methylidene)hydrazin-1-yl]-N-(2,3-dimethylphenyl)-6-(4-methylpiperidin-1-yl)-1,3,5-triazin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2144-1018

Molecular Formula

C33H35ClN8 (C33 H35 ClN8)

Compound Name

4-[(2E)-2-({1-[(4-chlorophenyl)methyl]-1H-indol-3-yl}methylidene)hydrazin-1-yl]-N-(2,3-dimethylphenyl)-6-(4-methylpiperidin-1-yl)-1,3,5-triazin-2-amine

IUPAC name

4-[(2E)-2-({1-[(4-chlorophenyl)methyl]-1H-indol-3-yl}methylidene)hydrazin-1-yl]-N-(23-dimethylphenyl)-6-(4-methylpiperidin-1-yl)-135-triazin-2-amine

SMILES

CC(CC1)CCN1c1nc(Nc2c(C)c(C)ccc2)nc(N/N=C/c2cn(Cc(cc3)ccc3Cl)c3c2cccc3)n1

InChI

InChI=1S/C33H35ClN8/c1-22-15-17-41(18-16-22)33-38-31(36-29-9-6-7-23(2)24(29)3)37-32(39-33)40-35-19-26-21-42(30-10-5-4-8-28(26)30)20-25-11-13-27(34)14-12-25/h4-14,19,21-22H,15-18,20H2,1-3H3,(H2,36,37,38,39,40)

InChI Key

SZHXDBFTRLUDHA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01051871

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

579.15

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

9.724

Distribution Coefficient, logD

9.722

Water Solubility, LogSw

-6.77

Polar Surface Area

65.836

Acid Dissociation Constant (pKa)

13.32

Base Dissociation Constant (pKb)

5.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

2144-1018 in Drug Discovery

Included in Screening Libraries

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with 2144-1018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2144-1018?
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What is the minimum amount of 2144-1018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2144-1018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2144-1018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2144-1018 available by request