2144-1021 Screening compound: 4-[(2Z)-2-{[3,5-dibromo-2-(prop-2-en-1-yloxy)phenyl]methylidene}hydrazin-1-yl]-N-(4-fluorophenyl)-6-(morpholin-4-yl)-1,3,5-triazin-2-amine

2144-1021 Screening compound: 4-[(2Z)-2-{[3,5-dibromo-2-(prop-2-en-1-yloxy)phenyl]methylidene}hydrazin-1-yl]-N-(4-fluorophenyl)-6-(morpholin-4-yl)-1,3,5-triazin-2-amine
2144-1021 Screening compound: 4-[(2Z)-2-{[3,5-dibromo-2-(prop-2-en-1-yloxy)phenyl]methylidene}hydrazin-1-yl]-N-(4-fluorophenyl)-6-(morpholin-4-yl)-1,3,5-triazin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 2144-1021
4-[(2Z)-2-{[3,5-dibromo-2-(prop-2-en-1-yloxy)phenyl]methylidene}hydrazin-1-yl]-N-(4-fluorophenyl)-6-(morpholin-4-yl)-1,3,5-triazin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2144-1021

Molecular Formula

C23H22Br2FN7O2 (C23 H22 Br2 FN7 O2)

Compound Name

4-[(2Z)-2-{[3,5-dibromo-2-(prop-2-en-1-yloxy)phenyl]methylidene}hydrazin-1-yl]-N-(4-fluorophenyl)-6-(morpholin-4-yl)-1,3,5-triazin-2-amine

IUPAC name

4-[(2Z)-2-{[35-dibromo-2-(prop-2-en-1-yloxy)phenyl]methylidene}hydrazin-1-yl]-N-(4-fluorophenyl)-6-(morpholin-4-yl)-135-triazin-2-amine

SMILES

C=CCOc(c(/C=N\Nc1nc(N2CCOCC2)nc(Nc(cc2)ccc2F)n1)cc(Br)c1)c1Br

InChI

InChI=1S/C23H22Br2FN7O2/c1-2-9-35-20-15(12-16(24)13-19(20)25)14-27-32-22-29-21(28-18-5-3-17(26)4-6-18)30-23(31-22)33-7-10-34-11-8-33/h2-6,12-14H,1,7-11H2,(H2,28,29,30,31,32)

InChI Key

WGOXVSJGILWORK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01330410

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

607.28

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

7.458

Distribution Coefficient, logD

7.457

Water Solubility, LogSw

-6.29

Polar Surface Area

80.302

Acid Dissociation Constant (pKa)

11.24

Base Dissociation Constant (pKb)

3.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

2144-1021 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 2144-1021 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2144-1021?
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What is the minimum amount of 2144-1021 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2144-1021
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2144-1021
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2144-1021 available by request