2145-0050 Screening compound: 2-[(2E)-2-[(2-hydroxynaphthalen-1-yl)methylidene]hydrazin-1-yl]-4-(methoxymethyl)-6-methylpyridine-3-carbonitrile

2145-0050 Screening compound: 2-[(2E)-2-[(2-hydroxynaphthalen-1-yl)methylidene]hydrazin-1-yl]-4-(methoxymethyl)-6-methylpyridine-3-carbonitrile
2145-0050 Screening compound: 2-[(2E)-2-[(2-hydroxynaphthalen-1-yl)methylidene]hydrazin-1-yl]-4-(methoxymethyl)-6-methylpyridine-3-carbonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound 2145-0050
2-[(2E)-2-[(2-hydroxynaphthalen-1-yl)methylidene]hydrazin-1-yl]-4-(methoxymethyl)-6-methylpyridine-3-carbonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2145-0050

Molecular Formula

C20H18N4O2 (C20 H18 N4 O2)

Compound Name

2-[(2E)-2-[(2-hydroxynaphthalen-1-yl)methylidene]hydrazin-1-yl]-4-(methoxymethyl)-6-methylpyridine-3-carbonitrile

IUPAC name

2-[(2E)-2-[(2-hydroxynaphthalen-1-yl)methylidene]hydrazin-1-yl]-4-(methoxymethyl)-6-methylpyridine-3-carbonitrile

SMILES

Cc(nc1N/N=C/c(c2ccccc2cc2)c2O)cc(COC)c1C#N

InChI

InChI=1S/C20H18N4O2/c1-13-9-15(12-26-2)17(10-21)20(23-13)24-22-11-18-16-6-4-3-5-14(16)7-8-19(18)25/h3-9,11,25H,12H2,1-2H3,(H,23,24)

InChI Key

GYUQUMSZAYZNJT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00363148

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

346.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.953

Distribution Coefficient, logD

3.948

Water Solubility, LogSw

-4.07

Polar Surface Area

72.194

Acid Dissociation Constant (pKa)

9.36

Base Dissociation Constant (pKb)

2.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

2145-0050 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with 2145-0050 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2145-0050?
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What is the minimum amount of 2145-0050 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2145-0050
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2145-0050
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2145-0050 available by request