2150-0536 Screening compound: (3E)-3-[(3-bromo-4-methoxyphenyl)methylidene]-1-(4-hydroxyphenyl)-5-phenyl-2,3-dihydro-1H-pyrrol-2-one

2150-0536 Screening compound: (3E)-3-[(3-bromo-4-methoxyphenyl)methylidene]-1-(4-hydroxyphenyl)-5-phenyl-2,3-dihydro-1H-pyrrol-2-one
2150-0536 Screening compound: (3E)-3-[(3-bromo-4-methoxyphenyl)methylidene]-1-(4-hydroxyphenyl)-5-phenyl-2,3-dihydro-1H-pyrrol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 2150-0536
(3E)-3-[(3-bromo-4-methoxyphenyl)methylidene]-1-(4-hydroxyphenyl)-5-phenyl-2,3-dihydro-1H-pyrrol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2150-0536

Molecular Formula

C24H18BrNO3 (C24 H18 BrNO3)

Compound Name

(3E)-3-[(3-bromo-4-methoxyphenyl)methylidene]-1-(4-hydroxyphenyl)-5-phenyl-2,3-dihydro-1H-pyrrol-2-one

IUPAC name

(3E)-3-[(3-bromo-4-methoxyphenyl)methylidene]-1-(4-hydroxyphenyl)-5-phenyl-23-dihydro-1H-pyrrol-2-one

SMILES

COc(ccc(/C=C(\C=C(c1ccccc1)N1c(cc2)ccc2O)/C1=O)c1)c1Br

InChI

InChI=1S/C24H18BrNO3/c1-29-23-12-7-16(14-21(23)25)13-18-15-22(17-5-3-2-4-6-17)26(24(18)28)19-8-10-20(27)11-9-19/h2-15,27H,1H3

InChI Key

YNFDKALQKRFRLI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01534968

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.32

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.893

Distribution Coefficient, logD

4.891

Water Solubility, LogSw

-4.56

Polar Surface Area

40.295

Acid Dissociation Constant (pKa)

9.89

Base Dissociation Constant (pKb)

3.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.20

2150-0536 in Drug Discovery

Included in Screening Libraries

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with 2150-0536 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2150-0536?
Check Price and Availability of 2150-0536, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2150-0536 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2150-0536
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2150-0536
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2150-0536 available by request