2180-0035 Screening compound: N'-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]-2-phenoxyacetohydrazide

2180-0035 Screening compound: N'-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]-2-phenoxyacetohydrazide
2180-0035 Screening compound: N'-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]-2-phenoxyacetohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 2180-0035
N'-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]-2-phenoxyacetohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2180-0035

Molecular Formula

C16H16N2O4 (C16 H16 N2 O4)

Compound Name

N'-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]-2-phenoxyacetohydrazide

IUPAC name

N'-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]-2-phenoxyacetohydrazide

SMILES

COc(cc(/C=N/NC(COc1ccccc1)=O)cc1)c1O

InChI

InChI=1S/C16H16N2O4/c1-21-15-9-12(7-8-14(15)19)10-17-18-16(20)11-22-13-5-3-2-4-6-13/h2-10,19H,11H2,1H3,(H,18,20)

InChI Key

HNDWHEJMMPURII-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00095993

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

300.31

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.120

Distribution Coefficient, logD

2.117

Water Solubility, LogSw

-2.69

Polar Surface Area

67.018

Acid Dissociation Constant (pKa)

9.56

Base Dissociation Constant (pKb)

4.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

2180-0035 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 2180-0035 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2180-0035?
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What is the minimum amount of 2180-0035 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2180-0035
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2180-0035
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2180-0035 available by request