2181-0846 Screening compound: N'-[(E)-(5-bromo-2-hydroxyphenyl)methylidene]-2-(4-bromonaphthalen-1-yl)acetohydrazide

2181-0846 Screening compound: N'-[(E)-(5-bromo-2-hydroxyphenyl)methylidene]-2-(4-bromonaphthalen-1-yl)acetohydrazide
2181-0846 Screening compound: N'-[(E)-(5-bromo-2-hydroxyphenyl)methylidene]-2-(4-bromonaphthalen-1-yl)acetohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 2181-0846
N'-[(E)-(5-bromo-2-hydroxyphenyl)methylidene]-2-(4-bromonaphthalen-1-yl)acetohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2181-0846

Molecular Formula

C19H14Br2N2O2 (C19 H14 Br2 N2 O2)

Compound Name

N'-[(E)-(5-bromo-2-hydroxyphenyl)methylidene]-2-(4-bromonaphthalen-1-yl)acetohydrazide

IUPAC name

N'-[(E)-(5-bromo-2-hydroxyphenyl)methylidene]-2-(4-bromonaphthalen-1-yl)acetohydrazide

SMILES

Oc(cc1)c(/C=N/NC(Cc(c2ccccc22)ccc2Br)=O)cc1Br

InChI

InChI=1S/C19H14Br2N2O2/c20-14-6-8-18(24)13(9-14)11-22-23-19(25)10-12-5-7-17(21)16-4-2-1-3-15(12)16/h1-9,11,24H,10H2,(H,23,25)

InChI Key

OVPLPFZLMKUODA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00747271

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.14

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.665

Distribution Coefficient, logD

5.652

Water Solubility, LogSw

-5.70

Polar Surface Area

51.617

Acid Dissociation Constant (pKa)

8.93

Base Dissociation Constant (pKb)

1.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

2181-0846 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with 2181-0846 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2181-0846?
Check Price and Availability of 2181-0846, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2181-0846 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2181-0846
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2181-0846
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2181-0846 available by request