2188-2186 Screening compound: (2Z)-2-(4-cyclopropyl-1,3-thiazol-2-yl)-3-(3-methylthiophen-2-yl)prop-2-enenitrile

2188-2186 Screening compound: (2Z)-2-(4-cyclopropyl-1,3-thiazol-2-yl)-3-(3-methylthiophen-2-yl)prop-2-enenitrile
2188-2186 Screening compound: (2Z)-2-(4-cyclopropyl-1,3-thiazol-2-yl)-3-(3-methylthiophen-2-yl)prop-2-enenitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound 2188-2186
(2Z)-2-(4-cyclopropyl-1,3-thiazol-2-yl)-3-(3-methylthiophen-2-yl)prop-2-enenitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2188-2186

Molecular Formula

C14H12N2S2 (C14 H12 N2 S2)

Compound Name

(2Z)-2-(4-cyclopropyl-1,3-thiazol-2-yl)-3-(3-methylthiophen-2-yl)prop-2-enenitrile

IUPAC name

(2Z)-2-(4-cyclopropyl-13-thiazol-2-yl)-3-(3-methylthiophen-2-yl)prop-2-enenitrile

SMILES

Cc1c(/C=C(\c2nc(C3CC3)cs2)/C#N)scc1

InChI

InChI=1S/C14H12N2S2/c1-9-4-5-17-13(9)6-11(7-15)14-16-12(8-18-14)10-2-3-10/h4-6,8,10H,2-3H2,1H3

InChI Key

SJQVNCWDSMFJOQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01540365

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

272.39

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

4.523

Distribution Coefficient, logD

4.523

Water Solubility, LogSw

-4.35

Polar Surface Area

28.299

Acid Dissociation Constant (pKa)

24.20

Base Dissociation Constant (pKb)

1.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

2188-2186 in Drug Discovery

Included in Screening Libraries

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 2188-2186 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2188-2186?
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What is the minimum amount of 2188-2186 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2188-2186
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2188-2186
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2188-2186 available by request