2189-1612 Screening compound: 4-[2-(difluoromethoxy)phenyl]-5-methyl-1,3-thiazol-2-amine

2189-1612 Screening compound: 4-[2-(difluoromethoxy)phenyl]-5-methyl-1,3-thiazol-2-amine
2189-1612 Screening compound: 4-[2-(difluoromethoxy)phenyl]-5-methyl-1,3-thiazol-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 2189-1612
4-[2-(difluoromethoxy)phenyl]-5-methyl-1,3-thiazol-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2189-1612

Molecular Formula

C11H10F2N2OS (C11 H10 F2 N2 OS)

Compound Name

4-[2-(difluoromethoxy)phenyl]-5-methyl-1,3-thiazol-2-amine

IUPAC name

4-[2-(difluoromethoxy)phenyl]-5-methyl-13-thiazol-2-amine

SMILES

Cc1c(-c(cccc2)c2OC(F)F)nc(N)s1

InChI

InChI=1S/C11H10F2N2OS/c1-6-9(15-11(14)17-6)7-4-2-3-5-8(7)16-10(12)13/h2-5,10H,1H3,(H2,14,15)

InChI Key

ZHTQLVQVTSYHCO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01419413

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

256.28

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

2.805

Distribution Coefficient, logD

2.805

Water Solubility, LogSw

-3.38

Polar Surface Area

38.232

Acid Dissociation Constant (pKa)

20.67

Base Dissociation Constant (pKb)

3.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.18

2189-1612 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

CNS BBB Library (22607 compounds)

Cardiovascular Library (22201 compounds)

GABA Library (7115 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Nervous system
  • Cardiovascular
  • Eye
  • Nervous system
  • Cardiovascular
Agro:
  • Agro
  • Agro
Targets:
  • GPCR
  • Ion Channels
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 2189-1612 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2189-1612?
Check Price and Availability of 2189-1612, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2189-1612 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2189-1612
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2189-1612
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2189-1612 available by request