2235-0517 Screening compound: N'-[(1E)-1-(3-hydroxyphenyl)ethylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide

2235-0517 Screening compound: N'-[(1E)-1-(3-hydroxyphenyl)ethylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide
2235-0517 Screening compound: N'-[(1E)-1-(3-hydroxyphenyl)ethylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 2235-0517
N'-[(1E)-1-(3-hydroxyphenyl)ethylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2235-0517

Molecular Formula

C22H19N5O2 (C22 H19 N5 O2)

Compound Name

N'-[(1E)-1-(3-hydroxyphenyl)ethylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide

IUPAC name

N'-[(1E)-1-(3-hydroxyphenyl)ethylidene]-2-[2-(pyridin-2-yl)-1H-13-benzodiazol-1-yl]acetohydrazide

SMILES

C/C(/c1cc(O)ccc1)=N\NC(Cn1c(-c2ncccc2)nc2c1cccc2)=O

InChI

InChI=1S/C22H19N5O2/c1-15(16-7-6-8-17(28)13-16)25-26-21(29)14-27-20-11-3-2-9-18(20)24-22(27)19-10-4-5-12-23-19/h2-13,28H,14H2,1H3,(H,26,29)

InChI Key

FXBKTRVKMPFARW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01535173

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.328

Distribution Coefficient, logD

3.327

Water Solubility, LogSw

-3.32

Polar Surface Area

71.222

Acid Dissociation Constant (pKa)

10.37

Base Dissociation Constant (pKb)

3.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

2235-0517 in Drug Discovery

Included in Screening Libraries

Dark Chemical Matter Library (18430 compounds)

Eccentric PPI Library (11937 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
  • Cyclic compounds
Mechanism of action:
  • PPI modulators
  • PPI modulators
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 2235-0517 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2235-0517?
Check Price and Availability of 2235-0517, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2235-0517 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2235-0517
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2235-0517
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2235-0517 available by request