2282-0174 Screening compound: 2-chloro-N'-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]benzohydrazide

2282-0174 Screening compound: 2-chloro-N'-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]benzohydrazide
2282-0174 Screening compound: 2-chloro-N'-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]benzohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 2282-0174
2-chloro-N'-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]benzohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2282-0174

Molecular Formula

C15H13ClN2O3 (C15 H13 ClN2 O3)

Compound Name

2-chloro-N'-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]benzohydrazide

IUPAC name

2-chloro-N'-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]benzohydrazide

SMILES

COc(cc(/C=N/NC(c(cccc1)c1Cl)=O)cc1)c1O

InChI

InChI=1S/C15H13ClN2O3/c1-21-14-8-10(6-7-13(14)19)9-17-18-15(20)11-4-2-3-5-12(11)16/h2-9,19H,1H3,(H,18,20)

InChI Key

BZBUQBKBQTZDSO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00750003

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

304.73

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.621

Distribution Coefficient, logD

2.586

Water Solubility, LogSw

-3.32

Polar Surface Area

59.733

Acid Dissociation Constant (pKa)

8.47

Base Dissociation Constant (pKb)

0.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.70

2282-0174 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 2282-0174 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2282-0174?
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What is the minimum amount of 2282-0174 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2282-0174
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2282-0174
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2282-0174 available by request