2293-3937 Screening compound: (2E)-N-(4,5-diphenyl-1,3-thiazol-2-yl)-3-phenylprop-2-enamide

2293-3937 Screening compound: (2E)-N-(4,5-diphenyl-1,3-thiazol-2-yl)-3-phenylprop-2-enamide
2293-3937 Screening compound: (2E)-N-(4,5-diphenyl-1,3-thiazol-2-yl)-3-phenylprop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 2293-3937
(2E)-N-(4,5-diphenyl-1,3-thiazol-2-yl)-3-phenylprop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2293-3937

Molecular Formula

C24H18N2OS (C24 H18 N2 OS)

Compound Name

(2E)-N-(4,5-diphenyl-1,3-thiazol-2-yl)-3-phenylprop-2-enamide

IUPAC name

(2E)-N-(45-diphenyl-13-thiazol-2-yl)-3-phenylprop-2-enamide

SMILES

O=C(/C=C/c1ccccc1)Nc1nc(-c2ccccc2)c(-c2ccccc2)s1

InChI

InChI=1S/C24H18N2OS/c27-21(17-16-18-10-4-1-5-11-18)25-24-26-22(19-12-6-2-7-13-19)23(28-24)20-14-8-3-9-15-20/h1-17H,(H,25,26,27)

InChI Key

IBFCLTJEAVTLNF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00296203

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.49

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.487

Distribution Coefficient, logD

6.487

Water Solubility, LogSw

-6.14

Polar Surface Area

33.390

Acid Dissociation Constant (pKa)

13.21

Base Dissociation Constant (pKb)

-2.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

2293-3937 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Epigenetics Focused Set (26518 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Phosphatases

References: we are preparing a list of scientific research reports with 2293-3937 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2293-3937?
Check Price and Availability of 2293-3937, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2293-3937 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2293-3937
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2293-3937
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2293-3937 available by request