2447-2845 Screening compound: 3-(3,5-dimethylphenyl)-2-(4-nitrophenyl)-1,3-thiazolidin-4-one

2447-2845 Screening compound: 3-(3,5-dimethylphenyl)-2-(4-nitrophenyl)-1,3-thiazolidin-4-one
2447-2845 Screening compound: 3-(3,5-dimethylphenyl)-2-(4-nitrophenyl)-1,3-thiazolidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 2447-2845
3-(3,5-dimethylphenyl)-2-(4-nitrophenyl)-1,3-thiazolidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2447-2845

Molecular Formula

C17H16N2O3S (C17 H16 N2 O3 S)

Compound Name

3-(3,5-dimethylphenyl)-2-(4-nitrophenyl)-1,3-thiazolidin-4-one

IUPAC name

3-(35-dimethylphenyl)-2-(4-nitrophenyl)-13-thiazolidin-4-one

SMILES

Cc1cc(N(C(c(cc2)ccc2[N+]([O-])=O)SC2)C2=O)cc(C)c1

InChI

InChI=1S/C17H16N2O3S/c1-11-7-12(2)9-15(8-11)18-16(20)10-23-17(18)13-3-5-14(6-4-13)19(21)22/h3-9,17H,10H2,1-2H3/t17-/m0/s1

InChI Key

UIHVNJZXRFNESI-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD01842444

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

328.39

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.257

Distribution Coefficient, logD

4.257

Water Solubility, LogSw

-4.40

Polar Surface Area

49.514

Acid Dissociation Constant (pKa)

14.79

Base Dissociation Constant (pKb)

-10.94

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.50

2447-2845 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 2447-2845 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2447-2845?
Check Price and Availability of 2447-2845, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2447-2845 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2447-2845
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2447-2845
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2447-2845 available by request