2466-0518 Screening compound: (2E)-N-[5-(1,3-benzoxazol-2-yl)-2-chlorophenyl]-3-phenylprop-2-enamide

2466-0518 Screening compound: (2E)-N-[5-(1,3-benzoxazol-2-yl)-2-chlorophenyl]-3-phenylprop-2-enamide
2466-0518 Screening compound: (2E)-N-[5-(1,3-benzoxazol-2-yl)-2-chlorophenyl]-3-phenylprop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 2466-0518
(2E)-N-[5-(1,3-benzoxazol-2-yl)-2-chlorophenyl]-3-phenylprop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2466-0518

Molecular Formula

C22H15ClN2O2 (C22 H15 ClN2 O2)

Compound Name

(2E)-N-[5-(1,3-benzoxazol-2-yl)-2-chlorophenyl]-3-phenylprop-2-enamide

IUPAC name

(2E)-N-[5-(13-benzoxazol-2-yl)-2-chlorophenyl]-3-phenylprop-2-enamide

SMILES

O=C(/C=C/c1ccccc1)Nc(cc(cc1)-c2nc(cccc3)c3o2)c1Cl

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.83

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.944

Distribution Coefficient, logD

5.944

Water Solubility, LogSw

-6.33

Polar Surface Area

39.229

Acid Dissociation Constant (pKa)

11.45

Base Dissociation Constant (pKb)

1.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

2466-0518 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

KRAS-Targeted Library (16000 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with 2466-0518 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2466-0518?
Check Price and Availability of 2466-0518, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2466-0518 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2466-0518
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2466-0518
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2466-0518 available by request