2860-1609 Screening compound: 2-[(1Z)-2-(4-chlorophenyl)ethenyl]-3-(3-methoxyphenyl)-3,4-dihydroquinazolin-4-one

2860-1609 Screening compound: 2-[(1Z)-2-(4-chlorophenyl)ethenyl]-3-(3-methoxyphenyl)-3,4-dihydroquinazolin-4-one
2860-1609 Screening compound: 2-[(1Z)-2-(4-chlorophenyl)ethenyl]-3-(3-methoxyphenyl)-3,4-dihydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 2860-1609
2-[(1Z)-2-(4-chlorophenyl)ethenyl]-3-(3-methoxyphenyl)-3,4-dihydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2860-1609

Molecular Formula

C23H17ClN2O2 (C23 H17 ClN2 O2)

Compound Name

2-[(1Z)-2-(4-chlorophenyl)ethenyl]-3-(3-methoxyphenyl)-3,4-dihydroquinazolin-4-one

IUPAC name

2-[(1Z)-2-(4-chlorophenyl)ethenyl]-3-(3-methoxyphenyl)-34-dihydroquinazolin-4-one

SMILES

COc1cccc(N(C(/C=C\c(cc2)ccc2Cl)=Nc2c3cccc2)C3=O)c1

InChI

InChI=1S/C23H17ClN2O2/c1-28-19-6-4-5-18(15-19)26-22(14-11-16-9-12-17(24)13-10-16)25-21-8-3-2-7-20(21)23(26)27/h2-15H,1H3

InChI Key

MRJAVPSFUVLGQR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02085020

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.85

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.846

Distribution Coefficient, logD

4.846

Water Solubility, LogSw

-5.07

Polar Surface Area

32.138

Acid Dissociation Constant (pKa)

33.29

Base Dissociation Constant (pKb)

4.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.30

2860-1609 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases

References: we are preparing a list of scientific research reports with 2860-1609 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2860-1609?
Check Price and Availability of 2860-1609, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2860-1609 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2860-1609
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2860-1609
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2860-1609 available by request