3286-0319 Screening compound: 2-(2,5-dimethyl-1H-indol-3-yl)-N'-[(1E)-1-(thiophen-2-yl)ethylidene]acetohydrazide

3286-0319 Screening compound: 2-(2,5-dimethyl-1H-indol-3-yl)-N'-[(1E)-1-(thiophen-2-yl)ethylidene]acetohydrazide
3286-0319 Screening compound: 2-(2,5-dimethyl-1H-indol-3-yl)-N'-[(1E)-1-(thiophen-2-yl)ethylidene]acetohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 3286-0319
2-(2,5-dimethyl-1H-indol-3-yl)-N'-[(1E)-1-(thiophen-2-yl)ethylidene]acetohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

3286-0319

Molecular Formula

C18H19N3OS (C18 H19 N3 OS)

Compound Name

2-(2,5-dimethyl-1H-indol-3-yl)-N'-[(1E)-1-(thiophen-2-yl)ethylidene]acetohydrazide

IUPAC name

2-(25-dimethyl-1H-indol-3-yl)-N'-[(1E)-1-(thiophen-2-yl)ethylidene]acetohydrazide

SMILES

C/C(/c1cccs1)=N\NC(Cc1c(C)[nH]c2c1cc(C)cc2)=O

InChI

InChI=1S/C18H19N3OS/c1-11-6-7-16-15(9-11)14(12(2)19-16)10-18(22)21-20-13(3)17-5-4-8-23-17/h4-9,19H,10H2,1-3H3,(H,21,22)

InChI Key

MMIDFCJRNBHLOB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01468312

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

325.43

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.230

Distribution Coefficient, logD

4.230

Water Solubility, LogSw

-4.34

Polar Surface Area

45.573

Acid Dissociation Constant (pKa)

10.78

Base Dissociation Constant (pKb)

1.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

3286-0319 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with 3286-0319 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 3286-0319?
Check Price and Availability of 3286-0319, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 3286-0319 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 3286-0319
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 3286-0319
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 3286-0319 available by request