3454-2890 Screening compound: 4-(4-benzylpiperidin-1-yl)-2-(pyridin-4-yl)quinazoline

3454-2890 Screening compound: 4-(4-benzylpiperidin-1-yl)-2-(pyridin-4-yl)quinazoline
3454-2890 Screening compound: 4-(4-benzylpiperidin-1-yl)-2-(pyridin-4-yl)quinazoline alternative view

Chemical Structure Depiction of ChemDiv screening compound 3454-2890
4-(4-benzylpiperidin-1-yl)-2-(pyridin-4-yl)quinazoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

3454-2890

Molecular Formula

C25H24N4 (C25 H24 N4)

Compound Name

4-(4-benzylpiperidin-1-yl)-2-(pyridin-4-yl)quinazoline

IUPAC name

4-(4-benzylpiperidin-1-yl)-2-(pyridin-4-yl)quinazoline

SMILES

C(C(CC1)CCN1c1nc(-c2ccncc2)nc2ccccc12)c1ccccc1

InChI

InChI=1S/C25H24N4/c1-2-6-19(7-3-1)18-20-12-16-29(17-13-20)25-22-8-4-5-9-23(22)27-24(28-25)21-10-14-26-15-11-21/h1-11,14-15,20H,12-13,16-18H2

InChI Key

KTDQOPQEUXVZTP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01897476

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.49

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.354

Distribution Coefficient, logD

6.170

Water Solubility, LogSw

-6.46

Polar Surface Area

30.795

Acid Dissociation Constant (pKa)

21.72

Base Dissociation Constant (pKb)

7.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

3454-2890 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with 3454-2890 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 3454-2890?
Check Price and Availability of 3454-2890, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 3454-2890 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 3454-2890
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 3454-2890
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 3454-2890 available by request