3635-1427 Screening compound: 2-methyl-5-{4-[(3-methylphenyl)amino]phthalazin-1-yl}benzene-1-sulfonamide

3635-1427 Screening compound: 2-methyl-5-{4-[(3-methylphenyl)amino]phthalazin-1-yl}benzene-1-sulfonamide
3635-1427 Screening compound: 2-methyl-5-{4-[(3-methylphenyl)amino]phthalazin-1-yl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 3635-1427
2-methyl-5-{4-[(3-methylphenyl)amino]phthalazin-1-yl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

3635-1427

Molecular Formula

C22H20N4O2S (C22 H20 N4 O2 S)

Compound Name

2-methyl-5-{4-[(3-methylphenyl)amino]phthalazin-1-yl}benzene-1-sulfonamide

IUPAC name

2-methyl-5-{4-[(3-methylphenyl)amino]phthalazin-1-yl}benzene-1-sulfonamide

SMILES

Cc1cccc(Nc2nnc(-c3cc(S(N)(=O)=O)c(C)cc3)c3ccccc23)c1

InChI

InChI=1S/C22H20N4O2S/c1-14-6-5-7-17(12-14)24-22-19-9-4-3-8-18(19)21(25-26-22)16-11-10-15(2)20(13-16)29(23,27)28/h3-13H,1-2H3,(H,24,26)(H2,23,27,28)

InChI Key

CQOTVEFMJWETJV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02163573

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.392

Distribution Coefficient, logD

4.383

Water Solubility, LogSw

-4.46

Polar Surface Area

82.364

Acid Dissociation Constant (pKa)

9.14

Base Dissociation Constant (pKb)

4.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

3635-1427 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

KRAS-Targeted Library (16000 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Phosphatases

References: we are preparing a list of scientific research reports with 3635-1427 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 3635-1427?
Check Price and Availability of 3635-1427, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 3635-1427 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 3635-1427
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 3635-1427
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 3635-1427 available by request