3643-3321 Screening compound: (2E)-2-cyano-N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}-3-phenylprop-2-enamide

3643-3321 Screening compound: (2E)-2-cyano-N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}-3-phenylprop-2-enamide
3643-3321 Screening compound: (2E)-2-cyano-N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}-3-phenylprop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 3643-3321
(2E)-2-cyano-N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}-3-phenylprop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

3643-3321

Molecular Formula

C21H18N4O4S (C21 H18 N4 O4 S)

Compound Name

(2E)-2-cyano-N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}-3-phenylprop-2-enamide

IUPAC name

(2E)-2-cyano-N-{4-[(34-dimethyl-12-oxazol-5-yl)sulfamoyl]phenyl}-3-phenylprop-2-enamide

SMILES

Cc1c(NS(c(cc2)ccc2NC(/C(/C#N)=C/c2ccccc2)=O)(=O)=O)onc1C

InChI

InChI=1S/C21H18N4O4S/c1-14-15(2)24-29-21(14)25-30(27,28)19-10-8-18(9-11-19)23-20(26)17(13-22)12-16-6-4-3-5-7-16/h3-12,25H,1-2H3,(H,23,26)

InChI Key

JJJTWIVYIAMYRR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02332858

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.46

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.321

Distribution Coefficient, logD

1.312

Water Solubility, LogSw

-3.79

Polar Surface Area

103.700

Acid Dissociation Constant (pKa)

5.40

Base Dissociation Constant (pKb)

-1.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

3643-3321 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

KRAS-Targeted Library (16000 compounds)

PI3K-Targeted Library (17255 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Agro:
  • Agro
Targets:
  • Kinases
  • Kinases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with 3643-3321 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 3643-3321?
Check Price and Availability of 3643-3321, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 3643-3321 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 3643-3321
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 3643-3321
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 3643-3321 available by request