3643-3369 Screening compound: 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}propanamide

3643-3369 Screening compound: 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}propanamide
3643-3369 Screening compound: 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 3643-3369
2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

3643-3369

Molecular Formula

C21H17N5O5S (C21 H17 N5 O5 S)

Compound Name

2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}propanamide

IUPAC name

2-(13-dioxo-23-dihydro-1H-isoindol-2-yl)-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}propanamide

SMILES

CC(C(Nc(cc1)ccc1S(Nc1ncccn1)(=O)=O)=O)N(C(c1c2cccc1)=O)C2=O

InChI

InChI=1S/C21H17N5O5S/c1-13(26-19(28)16-5-2-3-6-17(16)20(26)29)18(27)24-14-7-9-15(10-8-14)32(30,31)25-21-22-11-4-12-23-21/h2-13H,1H3,(H,24,27)(H,22,23,25)/t13-/m0/s1

InChI Key

OJBOOMQKBGEOBM-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD02351136

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.46

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.368

Distribution Coefficient, logD

0.613

Water Solubility, LogSw

-2.74

Polar Surface Area

113.414

Acid Dissociation Constant (pKa)

6.73

Base Dissociation Constant (pKb)

-1.67

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

9.50

3643-3369 in Drug Discovery

Included in Screening Libraries

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with 3643-3369 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 3643-3369?
Check Price and Availability of 3643-3369, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 3643-3369 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 3643-3369
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 3643-3369
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 3643-3369 available by request