3764-6593 Screening compound: 2-(3,4-dimethoxyphenyl)-N-(3-fluorophenyl)quinazolin-4-amine

3764-6593 Screening compound: 2-(3,4-dimethoxyphenyl)-N-(3-fluorophenyl)quinazolin-4-amine
3764-6593 Screening compound: 2-(3,4-dimethoxyphenyl)-N-(3-fluorophenyl)quinazolin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 3764-6593
2-(3,4-dimethoxyphenyl)-N-(3-fluorophenyl)quinazolin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

3764-6593

Molecular Formula

C22H18FN3O2 (C22 H18 FN3 O2)

Compound Name

2-(3,4-dimethoxyphenyl)-N-(3-fluorophenyl)quinazolin-4-amine

IUPAC name

2-(34-dimethoxyphenyl)-N-(3-fluorophenyl)quinazolin-4-amine

SMILES

COc(ccc(-c1nc2ccccc2c(Nc2cccc(F)c2)n1)c1)c1OC

InChI

InChI=1S/C22H18FN3O2/c1-27-19-11-10-14(12-20(19)28-2)21-25-18-9-4-3-8-17(18)22(26-21)24-16-7-5-6-15(23)13-16/h3-13H,1-2H3,(H,24,25,26)

InChI Key

NGLMXMPQWVVNGG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02643957

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.797

Distribution Coefficient, logD

5.191

Water Solubility, LogSw

-6.11

Polar Surface Area

43.066

Acid Dissociation Constant (pKa)

17.41

Base Dissociation Constant (pKb)

7.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

3764-6593 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

Antimitotic Tubulin Library (17355 compounds)

Epigenetics Focused Set (26518 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • Epigenetic
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with 3764-6593 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 3764-6593?
Check Price and Availability of 3764-6593, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 3764-6593 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 3764-6593
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 3764-6593
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 3764-6593 available by request