4189-0256 Screening compound: (4Z)-3-methyl-4-{[6-methyl-2-(morpholin-4-yl)quinolin-3-yl]methylidene}-1-phenyl-4,5-dihydro-1H-pyrazol-5-one

4189-0256 Screening compound: (4Z)-3-methyl-4-{[6-methyl-2-(morpholin-4-yl)quinolin-3-yl]methylidene}-1-phenyl-4,5-dihydro-1H-pyrazol-5-one
4189-0256 Screening compound: (4Z)-3-methyl-4-{[6-methyl-2-(morpholin-4-yl)quinolin-3-yl]methylidene}-1-phenyl-4,5-dihydro-1H-pyrazol-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 4189-0256
(4Z)-3-methyl-4-{[6-methyl-2-(morpholin-4-yl)quinolin-3-yl]methylidene}-1-phenyl-4,5-dihydro-1H-pyrazol-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4189-0256

Molecular Formula

C25H24N4O2 (C25 H24 N4 O2)

Compound Name

(4Z)-3-methyl-4-{[6-methyl-2-(morpholin-4-yl)quinolin-3-yl]methylidene}-1-phenyl-4,5-dihydro-1H-pyrazol-5-one

IUPAC name

(4Z)-3-methyl-4-{[6-methyl-2-(morpholin-4-yl)quinolin-3-yl]methylidene}-1-phenyl-45-dihydro-1H-pyrazol-5-one

SMILES

CC(/C(/C1=O)=C/c2cc3cc(C)ccc3nc2N2CCOCC2)=NN1c1ccccc1

InChI

InChI=1S/C25H24N4O2/c1-17-8-9-23-19(14-17)15-20(24(26-23)28-10-12-31-13-11-28)16-22-18(2)27-29(25(22)30)21-6-4-3-5-7-21/h3-9,14-16H,10-13H2,1-2H3

InChI Key

NUVWWZIECKDUBZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03196824

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.675

Distribution Coefficient, logD

4.675

Water Solubility, LogSw

-4.65

Polar Surface Area

45.212

Acid Dissociation Constant (pKa)

24.63

Base Dissociation Constant (pKb)

3.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

4189-0256 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with 4189-0256 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4189-0256?
Check Price and Availability of 4189-0256, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4189-0256 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4189-0256
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4189-0256
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4189-0256 available by request