4225-0268 Screening compound: 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-(5-methyl-4-phenyl-1,3-thiazol-2-yl)acetamide

4225-0268 Screening compound: 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-(5-methyl-4-phenyl-1,3-thiazol-2-yl)acetamide
4225-0268 Screening compound: 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-(5-methyl-4-phenyl-1,3-thiazol-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 4225-0268
2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-(5-methyl-4-phenyl-1,3-thiazol-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4225-0268

Molecular Formula

C20H15N3O3S (C20 H15 N3 O3 S)

Compound Name

2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-(5-methyl-4-phenyl-1,3-thiazol-2-yl)acetamide

IUPAC name

2-(13-dioxo-23-dihydro-1H-isoindol-2-yl)-N-(5-methyl-4-phenyl-13-thiazol-2-yl)acetamide

SMILES

Cc1c(-c2ccccc2)nc(NC(CN(C(c2c3cccc2)=O)C3=O)=O)s1

InChI

InChI=1S/C20H15N3O3S/c1-12-17(13-7-3-2-4-8-13)22-20(27-12)21-16(24)11-23-18(25)14-9-5-6-10-15(14)19(23)26/h2-10H,11H2,1H3,(H,21,22,24)

InChI Key

UGULRPZXBJXVFQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01849757

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.593

Distribution Coefficient, logD

3.593

Water Solubility, LogSw

-3.78

Polar Surface Area

63.186

Acid Dissociation Constant (pKa)

11.01

Base Dissociation Constant (pKb)

-1.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

4225-0268 in Drug Discovery

Included in Screening Libraries

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with 4225-0268 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4225-0268?
Check Price and Availability of 4225-0268, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4225-0268 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4225-0268
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4225-0268
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4225-0268 available by request