4290-0143 Screening compound: N-(2,4-difluorophenyl)-6-methyl-2-(morpholin-4-yl)-5-nitropyrimidin-4-amine

4290-0143 Screening compound: N-(2,4-difluorophenyl)-6-methyl-2-(morpholin-4-yl)-5-nitropyrimidin-4-amine
4290-0143 Screening compound: N-(2,4-difluorophenyl)-6-methyl-2-(morpholin-4-yl)-5-nitropyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 4290-0143
N-(2,4-difluorophenyl)-6-methyl-2-(morpholin-4-yl)-5-nitropyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4290-0143

Molecular Formula

C15H15F2N5O3 (C15 H15 F2 N5 O3)

Compound Name

N-(2,4-difluorophenyl)-6-methyl-2-(morpholin-4-yl)-5-nitropyrimidin-4-amine

IUPAC name

N-(24-difluorophenyl)-6-methyl-2-(morpholin-4-yl)-5-nitropyrimidin-4-amine

SMILES

Cc(nc(N1CCOCC1)nc1Nc(ccc(F)c2)c2F)c1[N+]([O-])=O

InChI

InChI=1S/C15H15F2N5O3/c1-9-13(22(23)24)14(19-12-3-2-10(16)8-11(12)17)20-15(18-9)21-4-6-25-7-5-21/h2-3,8H,4-7H2,1H3,(H,18,19,20)

InChI Key

YHAQZMZRZCFCBB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02996773

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.31

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.425

Distribution Coefficient, logD

3.424

Water Solubility, LogSw

-3.69

Polar Surface Area

71.308

Acid Dissociation Constant (pKa)

10.34

Base Dissociation Constant (pKb)

4.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

4290-0143 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Agro:
  • Agro
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 4290-0143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4290-0143?
Check Price and Availability of 4290-0143, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4290-0143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4290-0143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4290-0143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4290-0143 available by request