4333-6844 Screening compound: 3-(4-chlorophenyl)-2-(9-methyl-9H-carbazol-3-yl)-1,2,3,4-tetrahydroquinazolin-4-one

4333-6844 Screening compound: 3-(4-chlorophenyl)-2-(9-methyl-9H-carbazol-3-yl)-1,2,3,4-tetrahydroquinazolin-4-one
4333-6844 Screening compound: 3-(4-chlorophenyl)-2-(9-methyl-9H-carbazol-3-yl)-1,2,3,4-tetrahydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 4333-6844
3-(4-chlorophenyl)-2-(9-methyl-9H-carbazol-3-yl)-1,2,3,4-tetrahydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4333-6844

Molecular Formula

C27H20ClN3O (C27 H20 ClN3 O)

Compound Name

3-(4-chlorophenyl)-2-(9-methyl-9H-carbazol-3-yl)-1,2,3,4-tetrahydroquinazolin-4-one

IUPAC name

3-(4-chlorophenyl)-2-(9-methyl-9H-carbazol-3-yl)-1234-tetrahydroquinazolin-4-one

SMILES

Cn1c(ccc(C(Nc2c3cccc2)N(c(cc2)ccc2Cl)C3=O)c2)c2c2c1cccc2

InChI

InChI=1S/C27H20ClN3O/c1-30-24-9-5-3-6-20(24)22-16-17(10-15-25(22)30)26-29-23-8-4-2-7-21(23)27(32)31(26)19-13-11-18(28)12-14-19/h2-16,26,29H,1H3/t26-/m0/s1

InChI Key

XASODDQFCAAZPN-SANMLTNESA-N

MDL Number (MFCD)

MFCD03057284

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.93

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.318

Distribution Coefficient, logD

6.318

Water Solubility, LogSw

-6.32

Polar Surface Area

28.517

Acid Dissociation Constant (pKa)

13.67

Base Dissociation Constant (pKb)

-1.46

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

7.40

4333-6844 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

KRAS-Targeted Library (16000 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 4333-6844 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4333-6844?
Check Price and Availability of 4333-6844, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4333-6844 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4333-6844
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4333-6844
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4333-6844 available by request