4340-0528 Screening compound: N-(3-chlorophenyl)-2-{3-[(5Z)-2-(morpholin-4-yl)-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene]-2-oxo-2,3-dihydro-1H-indol-1-yl}acetamide

4340-0528 Screening compound: N-(3-chlorophenyl)-2-{3-[(5Z)-2-(morpholin-4-yl)-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene]-2-oxo-2,3-dihydro-1H-indol-1-yl}acetamide
4340-0528 Screening compound: N-(3-chlorophenyl)-2-{3-[(5Z)-2-(morpholin-4-yl)-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene]-2-oxo-2,3-dihydro-1H-indol-1-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 4340-0528
N-(3-chlorophenyl)-2-{3-[(5Z)-2-(morpholin-4-yl)-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene]-2-oxo-2,3-dihydro-1H-indol-1-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4340-0528

Molecular Formula

C23H19ClN4O4S (C23 H19 ClN4 O4 S)

Compound Name

N-(3-chlorophenyl)-2-{3-[(5Z)-2-(morpholin-4-yl)-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene]-2-oxo-2,3-dihydro-1H-indol-1-yl}acetamide

IUPAC name

N-(3-chlorophenyl)-2-{3-[(5Z)-2-(morpholin-4-yl)-4-oxo-45-dihydro-13-thiazol-5-ylidene]-2-oxo-23-dihydro-1H-indol-1-yl}acetamide

SMILES

O=C(CN(c(cccc1)c1/C1=C2/SC(N3CCOCC3)=NC2=O)C1=O)Nc1cccc(Cl)c1

InChI

InChI=1S/C23H19ClN4O4S/c24-14-4-3-5-15(12-14)25-18(29)13-28-17-7-2-1-6-16(17)19(22(28)31)20-21(30)26-23(33-20)27-8-10-32-11-9-27/h1-7,12H,8-11,13H2,(H,25,29)

InChI Key

AFCYTWITGLHJPI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02996399

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.95

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.052

Distribution Coefficient, logD

3.052

Water Solubility, LogSw

-3.70

Polar Surface Area

72.122

Acid Dissociation Constant (pKa)

11.08

Base Dissociation Constant (pKb)

0.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

4340-0528 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with 4340-0528 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4340-0528?
Check Price and Availability of 4340-0528, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4340-0528 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4340-0528
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4340-0528
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4340-0528 available by request