4340-1519 Screening compound: 1-[2-(dimethylamino)ethyl]-5-(furan-2-yl)-3-hydroxy-4-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-2-one

4340-1519 Screening compound: 1-[2-(dimethylamino)ethyl]-5-(furan-2-yl)-3-hydroxy-4-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-2-one
4340-1519 Screening compound: 1-[2-(dimethylamino)ethyl]-5-(furan-2-yl)-3-hydroxy-4-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 4340-1519
1-[2-(dimethylamino)ethyl]-5-(furan-2-yl)-3-hydroxy-4-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4340-1519

Molecular Formula

C17H18N2O4S (C17 H18 N2 O4 S)

Compound Name

1-[2-(dimethylamino)ethyl]-5-(furan-2-yl)-3-hydroxy-4-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-2-one

IUPAC name

1-[2-(dimethylamino)ethyl]-5-(furan-2-yl)-3-hydroxy-4-(thiophene-2-carbonyl)-25-dihydro-1H-pyrrol-2-one

SMILES

CN(C)CCN(C(c1ccco1)C(C(c1cccs1)=O)=C1O)C1=O

InChI

InChI=1S/C17H18N2O4S/c1-18(2)7-8-19-14(11-5-3-9-23-11)13(16(21)17(19)22)15(20)12-6-4-10-24-12/h3-6,9-10,14,21H,7-8H2,1-2H3/t14-/m0/s1

InChI Key

CIENHCCPHMMPGK-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD02986477

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

346.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.721

Distribution Coefficient, logD

0.602

Water Solubility, LogSw

-2.34

Polar Surface Area

58.539

Acid Dissociation Constant (pKa)

9.22

Base Dissociation Constant (pKb)

8.48

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

29.40

4340-1519 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 4340-1519 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4340-1519?
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What is the minimum amount of 4340-1519 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4340-1519
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4340-1519
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4340-1519 available by request