4340-1568 Screening compound: 3-hydroxy-4-(4-methoxybenzoyl)-5-[4-(propan-2-yl)phenyl]-1-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one

4340-1568 Screening compound: 3-hydroxy-4-(4-methoxybenzoyl)-5-[4-(propan-2-yl)phenyl]-1-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one
4340-1568 Screening compound: 3-hydroxy-4-(4-methoxybenzoyl)-5-[4-(propan-2-yl)phenyl]-1-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 4340-1568
3-hydroxy-4-(4-methoxybenzoyl)-5-[4-(propan-2-yl)phenyl]-1-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4340-1568

Molecular Formula

C26H24N2O4 (C26 H24 N2 O4)

Compound Name

3-hydroxy-4-(4-methoxybenzoyl)-5-[4-(propan-2-yl)phenyl]-1-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one

IUPAC name

3-hydroxy-4-(4-methoxybenzoyl)-5-[4-(propan-2-yl)phenyl]-1-(pyridin-2-yl)-25-dihydro-1H-pyrrol-2-one

SMILES

CC(C)c1ccc(C(C(C(c(cc2)ccc2OC)=O)=C(C2=O)O)N2c2ncccc2)cc1

InChI

InChI=1S/C26H24N2O4/c1-16(2)17-7-9-18(10-8-17)23-22(24(29)19-11-13-20(32-3)14-12-19)25(30)26(31)28(23)21-6-4-5-15-27-21/h4-16,23,30H,1-3H3/t23-/m0/s1

InChI Key

MMEKNTOZAXNHIM-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD02995478

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.832

Distribution Coefficient, logD

4.811

Water Solubility, LogSw

-4.48

Polar Surface Area

60.270

Acid Dissociation Constant (pKa)

8.72

Base Dissociation Constant (pKb)

-1.75

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

19.20

4340-1568 in Drug Discovery

Included in Screening Libraries

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 4340-1568 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4340-1568?
Check Price and Availability of 4340-1568, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4340-1568 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4340-1568
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4340-1568
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4340-1568 available by request