4358-4603 Screening compound: propyl 4-{[2-(4-nitrophenyl)quinazolin-4-yl]amino}benzoate

4358-4603 Screening compound: propyl 4-{[2-(4-nitrophenyl)quinazolin-4-yl]amino}benzoate
4358-4603 Screening compound: propyl 4-{[2-(4-nitrophenyl)quinazolin-4-yl]amino}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound 4358-4603
propyl 4-{[2-(4-nitrophenyl)quinazolin-4-yl]amino}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4358-4603

Molecular Formula

C24H20N4O4 (C24 H20 N4 O4)

Compound Name

propyl 4-{[2-(4-nitrophenyl)quinazolin-4-yl]amino}benzoate

IUPAC name

propyl 4-{[2-(4-nitrophenyl)quinazolin-4-yl]amino}benzoate

SMILES

CCCOC(c(cc1)ccc1Nc1nc(-c(cc2)ccc2[N+]([O-])=O)nc2ccccc12)=O

InChI

InChI=1S/C24H20N4O4/c1-2-15-32-24(29)17-7-11-18(12-8-17)25-23-20-5-3-4-6-21(20)26-22(27-23)16-9-13-19(14-10-16)28(30)31/h3-14H,2,15H2,1H3,(H,25,26,27)

InChI Key

MGTCGOQCHXNXQA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02369130

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.45

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

7.059

Distribution Coefficient, logD

7.001

Water Solubility, LogSw

-6.09

Polar Surface Area

82.235

Acid Dissociation Constant (pKa)

17.60

Base Dissociation Constant (pKb)

6.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

4358-4603 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antimitotic Tubulin Library (17355 compounds)

Epigenetics Focused Set (26518 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with 4358-4603 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4358-4603?
Check Price and Availability of 4358-4603, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4358-4603 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4358-4603
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4358-4603
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4358-4603 available by request